Epigenetic inheritance in ciliates
نویسندگان
چکیده
منابع مشابه
Epigenetic inheritance in the mouse
Acquired epigenetic modifications, such as DNA methylation or stable chromatin structures, are not normally thought to be inherited through the germline to future generations in mammals [1] [2]. Studies in the mouse have shown that specific manipulations of early embryos, such as nuclear transplantation, can result in altered patterns of gene expression and induce phenotypic alterations at late...
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with abiotic and biotic components of their surroundings. Whereas many and perhaps most of the encounters pass with transient changes at the molecular and metabolic levels, some have a profound impact on the phenotypic appearance of an organism and, more importantly, on the phenotypic appearance of their progeny. Since genetic changes are rare and random in nature, their influence on species or...
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The mechanisms by which stable gene expression patterns are inherited during cell division are not well understood. Chromatin is subject to a number of covalent modifications and it is generally believed that the transfer of these modifications between cell generations plays a critical role in inheritance, though how this occurs is a matter of debate. In one proposed model, replication of chrom...
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Recent fi ndings in the emerging fi eld of transgenerational epigenetic inheritance suggest that the lifestyle choices and experiences of an individual have biological implications for offspring not yet conceived. Studies show that diet, drugs, and even social experiences can lead to life-long changes in gene expression. Some changes in gene expression are passed down to future generations. The...
متن کاملTransgenerational epigenetic inheritance
Marisa Bartolomei University of Pennsylvania, USA Stefan Beck University College London, UK Christoph Bock University of Vienna, AT Liran Carmel Hebrew University of Jerusalem, IL Katharina Gapp Sanger Institute, Cambridge, UK Johannes Graeff Ecole Polytechnique Fédérale, Lausanne, CH Carlos Guerrero-Bosagna Linköping University, SE Eva Jablonka Tel Aviv University, IL Josep Chillarón Hospital ...
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ژورنال
عنوان ژورنال: Current Opinion in Microbiology
سال: 2009
ISSN: 1369-5274
DOI: 10.1016/j.mib.2009.09.012